The development of new methods for the treatment of allergic skin diseases is a priority area of practical dermatology. In the treatment of allergic skin diseases, much attention is paid to physiotherapy procedures. Among them, photodynamic therapy (PDT) occupies an important place in dermatological practice, which is a modern method of treatment, consisting in the introduction of a photoactive dye (photosensitizer) into biological tissue. Recently, in medical science, special interest has been attracted to semiconductor nanocrystals – especially silicon, since they have new physico-chemical properties that are promising for numerous applications.  137 patients with atopic dermatitis aged from 4 to 52 years were under observation. Among them , 84 were female and 54 were male. Clinical (SCORAD index), microbiological and statistical studies were performed in all patients.   

633 nm LED phototherapy was prescribed taking into account the clinical form and age of patients: with erythematous-squamous form, erythematous-squamous form with lichenization, pruriginous and lichenoid forms, 633 nm LED phototherapy of combined color (red + blue) with the use of fatiderm moisturizer, with exudative form - phototherapy of combined color with the use of essential tonic "Hydroray" and fatiderm cream for 20 minutes (for adults, for course No. 10), for children  -   LED phototherapy of combined color (red + blue) with the use of fatibaby emollient for 10 minutes (for course No. 5-7). Clinical observation of patients with AD receiving an innovative method of therapy showed an increase in therapeutic efficacy, expressed by clinical recovery in 73.1% of cases, a significant improvement – 23.1% (18). Thus, taking into account the high clinical effectiveness, it can be stated that an innovative method of combined phototherapy using the fatiderm line in patients with atopic dermatitis has been widely introduced into dermatological practice.

Mavlyanova Shakhnoza Zakirovna is a professor, has been working for more than 35 years at the Republican Scientific and Practical Medical Center of Dermatovenerology and Cosmetology of the Ministry of Health of the Republic of Uzbekistan, defended her doctoral thesis in 2005, under her leadership fundamental, applied and innovative grants were carried out in the field of topical problems of dermatology - atopic dermatitis, acne, opportunistic skin infections. He has more than 300 scientific publications, 12 patents for inventions, 8 monographs on allergic skin diseases. Under her leadership, 3 doctoral dissertations and 7 PhD dissertations were defended. He is an expert on dissertations in the specialty dermatovenerology at the Higher Attestation Commission of the Republic of Uzbekistan.